There is no such thing as a knee pain insole, although insoles can help certain types of knee pain. Knee pain can be caused by many issues. It is therefore best to find out what is causing it before you try treating it. The most common cause is osteoarthritis as a result of parts of the joint wearing away or muscle weakness around the knee. Supportive and cushioning insoles can help as can taping or a knee brace. Sometimes pain is located to around the kneecap (patella), which involves a slightly different joint from the main body of the knee. Knee pain just when running can often be helped with a supportive running insole, strengthening hip and knee muscles and by shortening the stride length.